Regenerative Biology & Tissue Engineering

Publications

Poellmann, M.J., Barton, K.L., Mishra, S,. Wagoner, A.J., Patterned Hydrogel Substrates for Cell Culture with Electrohydrodynamic Jet Printing. Macromol. Biosci. 2011, 11, 1164–1168

Hoelzle, D.J., Svientek, S.R., Alleyne, A.G., and Wagoner A.J., Design and Manufacture of Combinatorial Calcium Phosphate Bone Scaffolds. J. Biomech. Eng. 133, 101001 (2011)

The Non-receptor Tyrosine Kinase Lyn Controls Neutrophil Adhesion by Recruiting the CrkL-C3G Complex and Activating Rap1 at the Leading Edge Y. He, A. Kapoor, S. Cook, S. Liu, Y. Xiang, C.V. Rao, P.J.A. Kenis, F. Wang, J. Cell Sci., 2011, 124 (13), 2153-2164

Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow 86. C. Lin, V.L. Kolossov, G. Tsvid, L. Trump, J.J. Henry, J.L. Henderson, L.A. Rund, P.J.A. Kenis, L.B. Schook, H.R. Gaskins, G. Timp, Integrated Biology, 2011, in press

Liang, Y., Jeong, J., DeVolder, R., Cha, C., Wang, F., Tong, Y., & Kong, H.J. A Cell-Instructive Hydrogel to Regulate Malignancy of 3D Tumor Spheroids with Matrix Rigidity. Biomaterials (In press, 2011)

Cha, C., Kim, S.R. Jin, Y.S. & Kong, H. J.  Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production.  Biotechnology & Bioengineering (In press 2011, featured article)

Schmidt, J., Jeong, J.H. & Kong, H.J. Interplay of cell adhesion cues and curvature of a cell Adherent alginate microgel for multipotent stem cell culture. Tissue Engineering (In press 2011)

Cha, C., Jeong, J.H., Shim. J. & Kong, H.J. Tuning the dependency between stiffness and permeability of cell-encapsulating hydrogel with hydrophilic pendant chains  Acta Biomaterialia 7, 3719-3728 (2011)

DeVolder, R., H. Bae, J. Lee, & Kong, H.J. Directed blood vessel growth using angiogenic microfiber/microparticle composite patch. Advanced Materials 23, 3139-3143 (2011)

Cha, C., Kim, E.S., Kim, I.W. & Kong, H.J.  Integrative design of a Poly(Ethylene Glycol)-Poly(Propylene Glycol)-Alginate hydrogel to control three dimensional biomineralization  Biomaterials 32, 2695 (2011)

Liang Y. Jensen, T.W., Roy, E. J., Cha, C., DeVolder, R., J., Kohman, R.E., Zhang, B.Z., Textor, K.B., Rund, L.A., Schook, L.B., Tong, Y.W., & Kong, H.J. Tuning the non-equilibrium state of a drug-encapsulated poly(ethylene glycol) hydrogel for stem and progenitor cell mobilization Biomaterials 32, 2004 (2011)

Zorulutuna, P., Jeong, J., Kong, H.J., & Bashir, R.  Stereolithography-based hydrogel microenvironments for examining cellular interactions.  Advanced Functional Materials (In press, 2011)

Monaco, E., Bionaz, M., Hollister, S. Wheeler , M.B. 2011. Strategies for regeneration of the bone using porcine adult adipose-derived mesenchymal stem cells. Theriogenology 75:1381-1399.

Simon L, Hofmann MC and Cooke P (2011). Spermatogonial stem cells –an alternate source of pluripotent stem cells for regenerative medicine. In: Tissue Regeneration, InTech, in press

Garcia T and Hofmann MC (2011). Isolation of undifferentiated and early differentiating type A spermatogonia from POU5F1-GFP reporter mice. Methods Mol Biol, in press

Waheeb R and Hofmann MC (2011). Human spermatogonial stem cells: a possible origin for spermatocytic seminoma. Int J Andrology, 34: 296-305

Deborah E Leckband, Quint le Duc, Ning Wang, Johan de Rooij, Mechanotransduction at cadherin-mediated adhesions, Curr Opin Cell Biol (2011), doi:10.1016/j.ceb.2011.08.003

Carien M. Niessen, Deborah Leckband, Alpha S. Yap, Tissue Organization by Cadherin Adhesion Molecules: Dynamic Molecular and Cellular Mechanisms of Morphogenetic Regulation, Physiol Rev 91: 691–731, 2011;doi:10.1152/physrev.00004.2010

Li Y., Tamaki Yokohama-Tamaki and Tanaka T.S. (2011) “Short-term serum-free culture reveals that inhibition of Gsk3β induces the tumor-like growth of mouse embryonic stem cells”, PLoS ONE 6, e21355.

Microtopographically Patterned Surfaces Promote the Alignment of Tenocytes and Extracellular Collagen A. Kapoor, E.H.G. Caporali, P.J.A. Kenis, M.C. Stewart, Acta Biomateriala, 2010, 6, 2580-2589

Jeong, J.H., Schmidt, J., Cha, C.& Kong, H.J. Tuning responsiveness and structural integrity of the pH responsive hydrogel using poly(ethylene glycol) cross-linker Soft Matter 6, 3930 (2010)

Devolder, R. & Kong, H.J. Colloidal microgels for neovascularization Biomaterials 31, 6494 (2010)

Kohman, R., Cha, C., Zimmerman, S. G. & Kong, H.J. Tuning hydrogel properties and function using substituent effects. Soft Matter (Communication) 6, 2150 (2010)

Cha, C., Kim, S., Cao, L. & Kong, H.J.  Decoupled control of stiffness and permeability of cell-encapsulated poly(ethylene glycol) hydrogel. Biomaterials 31, 4864-4871 (2010)

Chan, V., Zorlutuna, P., Jeong, J. Kong, H.J. & Bashir, R. Three-Dimensional photopatterning of hydrogels using stereolithography for long-term cell encapsulation Lab on a Chip 10, 2062 (2010)

Hahn, L., Kong, H.J. & Mooney, D.J. Polycation structure mediates expression of lyophilized polycation-pDNA complexes.  Macromolecular. Biosciences 10, 1210-1215 (2010)

Kim, D., Monaco, E., Maki, A., Sobriera de Lima, A., Kong, H.J. & Wheeler M.B. Morphologic and transcriptomic comparison of adipose- and bone-marrow-derived porcine stem cells cultured in alginate hydrogels. Cell & Tissue Research 341, 359-370 (2010)

Zill, A., Rutz, A.L., Kohman, R.E., Alkilany, A.M., Murphy, C.J., Kong, H.J., & Zimmerman S.C. Clickable polyglycerol hyperbranched polymers and their application to gold nanoparticles and acid-labile nanocarriers.  Chemical Communication 47, 1279-1281 (2010)

Monaco, E., Bionaz, M., Lima, A.S., Hurley, W.L.  Wheeler, M.B. 2010. Internal Controls for Quantitative Polymerase Chain Reaction of Porcine Adult Mesenchymal Stem Cells. Stem Cell Research & Therapy, 1:7 doi:10.1186/scrt7

Simon L, Ekman GC, Carnes K, Zhang Z, Murphy T, Murphy KM, Hess RA, Cooke PS and Hofmann MC. (2010). The transcription factor Etv5 regulates Sertoli cell chemokines involved in maintaining stem/progenitor spermatogonia in the niche. Stem Cells, 28:1882-92

Braydich-Stolle LK, Lucas B, Schrand A, Murdock RC, Lee T, Schlager J, Hussain S and Hofmann MC (2010). Silver nanoparticles disrupt GDNF/Fyn signaling in spermatogonial stem cells. Toxicol. Sci.116:577-589

Kokkinaki M, Lee TL, He Z, Jiang J, Golestaneh N, Hofmann MC, Chan WY, Dym M. (2010). Age affects gene expression in mouse spermatogonial stem/progenitor cells. Reproduction, 139:1011-1020

Chowdhury F., Li Y., Poh Y-C., Yokohama-Tamaki T., Wang N., and Tanaka T.S. (2010) “Soft substrates promote self-renewal of embryonic stem cells by maintaining low tractions”, PLoS ONE 5, e15565.

Cadherin and Integrin Regulation of Epithelial Cell Migration J. Silvestre, P.J.A. Kenis, D.E. Leckband, Langmuir, 2009, 25 (17), 10092-10099

Microfluidic Generation of Lipidic Mesophases for Membrane Protein Crystallization. S.L. Perry, G.W. Roberts, J.D. Tice, R.B. Gennis, P.J.A. Kenis, Cryst. Growth & Design, 2009, 9 (6), 2566-2569

Chu, C., Devolder, R., Scaffer, B. & Kong, H.J. Quantitatively analyzing the cross-linked structure of microgels using fluorescent probes. Polymer 50:5288-5292 (2009).

Cha, C. Kohman, R., & Kong, H.J. Biodegradable Polymer Cross-linker: Independent control of stiffness, toughness and degradation rate of hydrogel. Advanced Functional Materials 19; 3056-3062 (2009)

Chu, C., Schmidt, J.J., Carne, K., Zhang, Z., Kong, H.J.*, Hofmann, M-C.* Three-Dimensional synthetic niche components to control germ cell proliferation. Tissue Engineering A 15, 255-262 (2009) [*Co-corresponding authors]

Sung, J., Barone, P., Kong, H.J., Strano, M. Sequential delivery of dexamethasone and VEGF to control local tissue response for carbon nanotube fluorescence based micro-capillary implantable sensors Biomaterials 30, 622-631 (2009)

Engineering Redox-Sensitive Linkers for Genetically Encoded FRET-based Biosensors. Vladimir L. Kolossov, Bryan Q. Spring, Anna Sokolowski, John E. Conour, Robert M. Clegg, Paul J. A. Kenis, H. Rex Gaskins, Experimental Biology and Medicine, 2008, 233, 238-248SEBM’s 2008 Alan MacDiarmid Best Paper Award in the interdisciplinary research category

Schmidt, J.J. Rowley, J. Kong, H.J. "Hydrogels used for cell-based drug delivery," Journal of Biomedical Materials Research 87A 1113-1122 (2008)

Kong, H. J., Kim, E.S., Huang, Y. C., & Mooney, D. J. Design of biodegradable hydrogel for the local and sustained delivery of angiogenic plasmid DNA Pharmaceutical Res. 25: 1230-1238(2008)

Kong, H. J., Kim, C.J., Huebsch, N. D., Weitz, D., & Mooney, D. J. Non-invasive probing of the spatial organization of polymer chains in hydrogels using Fluorescence Resonance Energy Transfer (FRET). Journal of the American Chemical Society 129: 4518-4519 (2007)

Twists and Turns in the Development and Maintenance of Mammalian Small Intestine Epithelium. A.L. Hauck, K.S. Swanson, P.J.A. Kenis, D.E. Leckband, H.R. Gaskins, L.B. Schook, Birth Defects Research (Part C), 2005, 75, 58-71 (review)

Regiospecific Control of Gene Expression in Cells Cultured on Two-component Counter Gradients of Extracellular Matrix Proteins. R. Gunawan, E.R. Choban, J. Conour, J. Silvestre, H.R. Gaskins, L.B. Schook, P.J.A. Kenis, D.E. Leckband, Langmuir, 2005, 21, 3061-3068

Quint le Duc, Quanming Shi, Iris Blonk, Arnoud Sonnenberg, Ning Wang, Deborah Leckband, Johan de Rooij, Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner, J. Cell Biol. Vol. 189 No. 7 1107–1115, www.jcb.org/cgi/doi/10.1083/jcb.201001149